Finally, if the target autoantigen in mouse and human β cells were the same, the prevention of type 1 diabetes in the NOD mouse would rapidly be followed by comparable immunologic prediction and ...

But there is much more work to be done, he added. “While in this study we showed that the human immune cells that were specific to human insulin B:9-23 were reacting to the P. distasonis peptide and ...

CellTrans has claimed the first FDA approval for a cell therapy used to treat type 1 diabetes, consisting of insulin-producing islet beta cells taken from deceased donors. The Chicago-based ...

In addition, we utilize clinically relevant mouse models of autoimmunity, such as Type 1 Diabetes, to understand how autoimmune responses are initiated and sustained. Our ongoing and future research ...