This application note explores optimized culturing conditions for precision-cut slices (PCS) of non-small cell lung carcinoma ...

Cytokine signaling from the tumor microenvironment can allow leukemia ... Clinically, imatinib resistance in Ph+ ALL presents a complex and perhaps mixed set of mechanisms. Unlike in mice ...

Recent advances in immunotherapy research have revealed crucial roles for new immune cells in combating cancer, leading to ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in ...

Brain tumors pose significant treatment challenges due to their complex structure and the sensitive location within the brain. Surgical options are often limited by the brain's intricate layout, and ...

Discover how cancer cells survive in low-glucose environments and evade chemotherapy-induced death. New study sheds light on ...

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative ...

In recent decades, immunotherapy has transformed cancer treatment, offering effective options for diseases once considered ...

Natural killer (NK) cells play an important role in the innate immune response to cancer and viral infections, and their ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine.