The cancer microenvironment, or tumour microenvironment, describes the non-cancerous cells present in the tumour. These include fibroblasts, immune cells and cells that comprise the blood vessels.

this abnormal tumor microenvironment does not impair tumor-cell survival. In conclusion, the spatial and temporal heterogeneities in blood supply and vessel permeability along with poor lymphatic ...

The so-called tumor microenvironment (TME) is known to be the environment around the tumor and includes the encircling blood vessels, fibroblasts, signaling molecules, immune cells and the ...

Aside from providing oxygen and nutrients to the tumor, blood vessels also secrete angiocrine factors. This study revealed that the factor Sfrp1, produced by vascular endothelial cells ...

as presented last month in Rome at the 31st Annual Congress of the European Society of Gene and Cell Therapy (ESGCT). Some of these advances are taking advantage of the conditions of the tumor ...

Another key player is the tumor “microenvironment”— the cellular environment in which a tumor lives. The microenvironment consists of tissue, blood vessels, immune cells, fibroblasts, and other ...

Judah Folkman's most significant findings in a career rife with discoveries was that cancerous tumors appear to trigger the growth of new blood vessels, which the tumors need to thrive.

Targeting and customizing blood vessels in tumors to increase T cell infiltration and maintain their function may represent the next breakthrough in cancer therapy. The European Research Council ...

And they now believe targeted cancer drugs may be able to treat it. AVM, which usually worsens over time, can cause swelling and disfigurement. An AVM is an abnormal collection of blood vessels ...

A significant obstacle in treating ovarian cancer is the tumor microenvironment—the complex ecosystem of cells, molecules and ...