Stewart, C. R. et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nature Immunology 11,155–161 (2010) doi:10.1038/ni.1836. Takeuchi ...

Toll-like receptors (TLRs) are a family of pattern recognition receptors that recognize conserved structures that are associated with infection or tissue damage. Activation of TLRs promotes ...

Toll-like receptors (TLRs) are one of the largest and ... TLRs on the plasma membrane (TLR1, 2, 4 and 6) detect viral proteins, which are released in the extracellular environment, while endosomal ...

Interleukin-1 receptor-associated kinase 4 is critical in the modulation of inflammatory responses through Toll-like receptor and IL-1R signaling.