This article was originally published with the title “ The Three-Dimensional Structure of a Protein Molecule ” in Scientific American Magazine Vol. 205 No. 6 (December 1961), p. 96 doi:10.1038 ...

so different proteins have different three-dimensional shapes. The three-dimensional shape of a protein determines its function. This is because proteins form attachments and interact with many ...

As advances in x-ray crystallography, the traditional method of determining protein structures, made available the first large wave of three-dimensional ... called structure-based drug design.

Proteins are composed of one or more chains of amino acids, which are linked together by peptide bonds and folded into specific three-dimensional structures. Proteins have four levels of structure: ...

to build the three-dimensional atomic structure of large protein complexes, work recently published in Nature Communications.

The human body contains proteins that are designed to protect us from cancerous growths. Like most proteins, to do their job properly, these “guardians” have to fold into a specific three-dimensional ...

Based on a protein’s three-dimensional surface structure, the algorithm designs molecules that bind specifically to the protein according to the lock- and-key principle, so they can interact ...

Determining a protein’s three-dimensional structure based solely on its one-dimensional amino acid sequence has stood as a grand challenge in the field of biology for over half a century.