Metabolic syndrome, including obesity and diabetes, intersects with male infertility due to hypogonadism. Adipose tissue secretes leptin and estrogen, both of which modulate male reproduction.

This case suggests that aromatase inhibition could be an effective treatment for infertility in the setting of obesity-related hypogonadotropic hypogonadism. Data concerning the safety and ...

Normosmic idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome are rare congenital forms of secondary hypogonadism characterized by delayed or absent sexual development.

such as Klinefelter’s syndrome. This type of testosterone deficiency is known as primary testicular failure or primary hypogonadism. Other men, such as men with obesity or pituitary dysfunction ...

Bardet-Biedl syndrome, which is diagnosed clinically, affects approximately 4,000 to 5,000 people in the US. People living with BBS may experience insatiable hunger, also known as hyperphagia, and ...