Get detailed information on Hydrochlorothiazide and Spironolactone, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.
The landmark Randomized Aldactone Evaluation Study (RALES), published in 1999, showed that spironolactone, a potassium-sparing diuretic, improves outcomes in patients with severe heart failure.