Crystal structures of Mtb RNAP bound to rifampin (left) and Mtb RNAP bound to an AAP (right) show the Mtb RNAP interactions. Gray ribbons, Mtb RNAP backbone; gray, cyan, and green sticks ...
MDR TB is caused by germs that are resistant to two or more of the main tuberculosis drugs -- isoniazid and rifampin.
We did a systematic review and meta-analysis of trials of treatment for rifampicin-susceptible tuberculosis to evaluate the ...