The most common nonfamilial forms of amyloidosis that involve the kidney are the AL (amyloid light chain) and AA (serum amyloid A) types. These two forms require different treatment strategies ...

However, only two related conditions are associated with the simultaneous presence of Bence Jones proteinuria and heavy albuminuria: renal AL amyloidosis and LCDD. [20] It is not uncommon for ...

Of these, 5 had renal biopsy–confirmed renal AL amyloidosis, and 1 had LCDD. All 5 patients with AL amyloidosis had λ Bence Jones proteinuria. The only patient in our study with renal LCDD had ...

UK: A recent retrospective cohort study has highlighted the critical role of kidney function in patients diagnosed with ...

Preclinical studies have shown AT-02 is able to bind to multiple amyloid types and can induce macrophage mediated amyloid phagocytosis and removal. The Food and Drug Administration has granted Orphan ...

Discover how kidney function decline in ATTR-CM patients predicts higher mortality, highlighting its role as a critical marker in disease management and care optimisation.

In this retrospective cohort study, decline in kidney function was frequent in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) and was consistently associated with an increased risk of ...

One of the most serious complications of rheumat0logic and autoimmune diseases can be prevented with biologic drugs, a single-center chart review suggested, and some such products may be more ...