Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin organization and cell cycle state, including quiescence. Gene expression is important because a specific ...

coli? The answer lies in the difference in gene expression and regulation used. Regulation of transcription in eukaryotes is a result of the combined effects of structural properties (how DNA is ...

Gene regulation in multicellular eukaryotes is complex, with many layers of regulation. Two fundamental mechanisms of gene regulation involve transcription factors and microRNAs, a large class of ...

Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within ...

When gene regulation fails, or specific genes are altered through mutation, the body is more predisposed to diseases such as cancer, Alzheimer's, and autoimmune disorders. Now, for the first time ...