Most cancer treatments – from chemotherapies to engineered immune cells – have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor ...

New research has revealed the diverse assembly and regulation of Type-A GABA receptors (GABAARs), which are crucial for ...

Newly discovered mechanism helps detach and recycle parts of cellular canal membranes as needed – models developed using ...

GC-A is a type of single-pass transmembrane receptor protein that spans the cell membrane, connecting a binding region on the cell surface to an interior signaling domain, allowing it to transmit ...

Researchers from the Institute for Neurosciences (IN), a joint center of the Miguel Hernández University of Elche (UMH) and ...

corresponding author Shi and an international research team introduced the concept of customised virus receptors, a modular chimeric protein they compared to “Lego blocks”. “The modular ...

This bioinformatics-assisted review describes key biological elements of known pathways, such as the forkhead box protein ...

More information: Bone marrow macrophage derived GPNMB protein binds to orphan receptor GPR39 and plays a critical role in cardiac repair, Nature Cardiovascular Research (2024).

Targeted therapy revolutionized cancer treatment, with gene fusions leading the way when the FDA approved imatinib in 2001 to ...

“We are pleased to share data describing the use of megalin’s endogenous receptor-mediated endocytosis ... first megalin-STRIKERs that target SLC proteins. Modulating function of specific ...