In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling ... proteins bind to histones and nucleosomal DNA, and their binding to these ...

So how does the cell know where to uncoil in a process called chromatin remodeling ... through posttranslational modifications of histone proteins, which actually change the conformation of ...

By revealing how such dynamics could go awry in mutant variants of the remodeler proteins ... binding events preferentially ...