Researchers have found an ancient protein fold that might explain how life’s basic building blocks became the complex systems ...

RNAs have been shown to have a function in protein secretion after thousands more binding targets were identified using a ...

Using CRISPR-based microRaft and gRNA identification, they screened for RNA-binding proteins that may contribute to CHMP7 ...

University of Chicago scientists have expanded our understanding of snoRNAs, discovering their extensive influence on ...

Dynamic, reversible modifications of DNA and RNA regulate how genes are expressed and transcribed, which can influence ...

Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, United States This important study employed multiple orthogonal techniques and ...

RNA transcription makes an efficient control point because many proteins can be made from a single mRNA molecule ... copies of the regulatory protein binding sites exist within the genome of ...

The study was the only one from Canadian researchers featured in the recent RNA-focused issue of Molecular Cell. It presents RNA-binding maps for many proteins – a valuable resource for ...

We use a variety of biochemistry, molecular and cellular biology technologies in ... For example, we use plant proteins (e.g. Cry2) that, when attached to disease-linked RNA-binding proteins, cause ...

Dr Paul Clarke’s Group is a key part of the Centre for Cancer Drug Discovery and focuses on the mechanisms of molecular cancer therapies and particularly targeting the addiction or dependency of ...

Interestingly, mRNA is not particularly stable by nature and would be degraded prematurely without molecular caps ... target ...