Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, United States This important study employed multiple orthogonal techniques and ...
A new study has explored the RNA-binding mechanisms of the antiviral protein TRIM25. TRIM25 (green, left) finds its way to the same locations in the cell where a virus (red, middle) replicates.
"We wanted to understand the role of TRIM25's RNA binding in antiviral defence." TRIM25 belongs to a large family of enzymes that can tag other proteins in the cell with a small protein called ...