There was no theoretical need to explain existing phenomena in terms of new mechanisms or new ... in terms of the activities of RNA-binding regulatory proteins. Our search for additional microRNAs ...
Finally, it is not at all clear why a substrate binding pocket ... Nevertheless, the mechanism by which the three domains of the protein and domain IV of SRP RNA work in concert to recognize ...
We are interested in understanding the mechanisms and consequences of this regulation, from how RNA binding proteins and signaling pathways coordinate RNA processing networks to the functional ...
HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...
A new study has explored the RNA-binding mechanisms of the antiviral protein TRIM25. TRIM25 (green, left) finds its way to the same locations in the cell where a virus (red, middle) replicates.
Neurobiology, Neurodegeneration and Repair Laboratory, National Eye Institute, National Institutes of Health, Bethesda, United States This important study employed multiple orthogonal techniques and ...
and thus it is not clear how conformation-specific subunit-subunit binding interactions can be. Furthermore, how can BMV proteins that assemble with conformational specificity to form T=3 empty ...
These rRNAs are involved in mRNA binding and decoding. Large Subunit rRNAs ... which catalyzes the formation of peptide bonds between amino acids during protein synthesis. This discovery led to the ...
Huang Chengdong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) revealed the molecular mechanism ... binding modes of E-cadherin-catenin ...