This image illustrates the chemical structure of a purine molecule, highlighting the numbering of the carbon and nitrogen atoms. The purine structure consists of a pyrimidine ring (positions 1 to 6) ...

This diagram depicts the chemical structure of pyrimidine, a six-membered aromatic ring with two nitrogen atoms at positions 1 and 3 (highlighted in blue). The remaining positions are occupied by ...

Vitamin B13 or Orotic acid is an intermediate in pyrimidine metabolism, primarily used for metabolization of folic acid and vitamin B12. Vitamin B13 improves myocardial purine and pyrimidine ...

[31] MTX was designed to be a close analog of FA and to block the folate-dependent steps in de novo purine and pyrimidine biosynthesis (Figure 1).