which inhibits the arginine methyltransferase 5 (PRMT5) protein. Pinometostat has shown an acceptable safety profile in phase I clinical trials for the treatment of acute leukemia; its effects ...

Beijing Double-Crane Runchuang Technology Co. Ltd. has disclosed protein arginine N-methyltransferase 5 (PRMT5) inhibitors reported to be useful for the treatment of cancer. BioWorld Science Cancer ...

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announced the nomination of ISM1745, a potentially best-in ...