thus turning off expression of a gene. Positive regulation by TFs that are activators is common in eukaryotes. Considering the restrictive transcriptional ground state, it is logical that positive ...

How Is Gene Expression Regulated ... Transcript processing provides an additional level of regulation for eukaryotes, and the presence of a nucleus makes this possible. In prokaryotes, translation ...

The genome contains tens of thousands of genes. Like a gigantic orchestra, their interaction is the basis for all vital ...

Scientists at the University of California, Irvine, have discovered that nuclear speckles, a membraneless organelle within ...

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...

This important study of regulatory elements and gene expression in the craniofacial region of the fat-tailed dunnart shows that, compared to placental mammals, marsupial craniofacial tissue develops ...

They seek to understand how cells modulate gene expression by modulating chromatin and DNA organization. Fred Hutch researchers have done pioneering work in the areas of gene regulation, chromatin ...

The molecular mechanisms of transcription within a chromatin environment will be discussed, along with the role of RNA processing and post-transcriptional regulation in gene expression, and their ...