Therapeutic monoclonal antibodies (mAbs) are a class of antibody drugs that are highly uniform and have pharmacological effects against a single epitope obtained through molecular biology. In the ...
Assessing the pharmacokinetics (PK) of antibody-drug conjugates (ADCs) in both preclinical and clinical settings is crucial for their development. Biotransformation processes can lead to the ...
Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs ... human immunoglobulin gamma monoclonal antibodies (hIgG mAbs) are a most promising ...