The FDA approved the PI3K-pathway inhibitor inavolisib (Itovebi ... and creatinine; and stomatitis; diarrhea; fatigue; rash; ...
Other possible problems include heart attacks, stroke, stomachaches, internal bleeding, ulceration and skin reactions.
HOUSTON -- Two-thirds of patients with PI3K -mutant brain metastases responded to the maximum tolerated dose (MTD) of the ...
In the absence of head-to-head studies, oncologists are looking across pivotal trials and are encouraged by Itovebi's safety and efficacy versus Piqray.
13 In a safety analysis, TEAEs included diarrhea (48.8%), nausea (29.5% ... Data accumulated to date with respect to various PI3K inhibitors suggest improved response rates and longer survival ...
Infinity Pharmaceuticals has gained access to Intellikine's portfolio of phosphoinositide 3-kinase-δ (PI3Kδ) and PI3Kγ inhibitors for inflammation and oncology indications through an exclusive ...