The hepatic cytochrome P450 system metabolizes it extensively, and ketamine pretreatment can cause hepatic microsomal enzyme induction and tolerance. Norketamine, the primary metabolite ...

will be associated with less therapeutic variability than warfarin because its structure precludes it from being metabolized by the cytochrome P450 (CYP450) system. By contrast, warfarin is ...

题为 “A nucleobase-driven P450 peroxidase system enables regio- and stereo-specific formation of C ? C and C ? N bonds” 近日，国际权威期刊《Proceedings of the National Academy of Sciences》在线发表了武汉大学药学院张郑宇 ...

The multifaceted functions of P450 genes in chemical modification of prenyl indole alkaloids and thermophilic fungal adaption to cold stress. News organizations may use or redistribute this image ...