Mixed results were seen in the studies evaluating the use of opioid antagonists for the prevention of OIP. While oral naltrexone provided some benefit in some studies and its use would be more ...

Connecticut College is committed to the health and safety of its community members and strives to prevent the harm that may result from the misuse and abuse of opioid substances.

This is your brain on drugs,” the old anti-drug admonition says, and now a new study has found there’s something to ...

Avoid concomitant mixed agonist/antagonist opioids (eg, butorphanol, nalbuphine, pentazocine) or partial agonist (eg, buprenorphine); may reduce effects and/or precipitate withdrawal symptoms.

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive ...

This manuscript represents a fundamental contribution demonstrating that fentanyl-induced respiratory depression can be reversed with a peripherally-restricted mu opioid receptor antagonist. The paper ...

Young Australians are taking the opioid reversal drug naloxone with them on nights out. We've unpacked what it is and how it ...

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive ...

Avoid concomitant mixed agonist/antagonist opioids (eg, butorphanol, nalbuphine, pentazocine) or partial agonist (eg, buprenorphine); may reduce effects and/or precipitate withdrawal symptoms.

Opioids target the opioid receptors in the brain ... fentanyl is sold illegally through illicit drug channels and sometimes is mixed with other drugs like cocaine and heroin.

Purpose. Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...