However, under the low stringency conditions required for short nucleic acid probes to form stable interaction, the longer single-stranded targets are able to engage in secondary structure.

Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos ... Additional advantages: Access LNA probes for multiplexing with a full suite of fluorophores.

Ten years ago, a pair of scientists described a new kind of probe for quantifying nucleic acids that could do it in real-time and in solution 1. No purification, no gels, no radioactivity (and no ...

Quantitative real-time PCR (qPCR) is the tool of choice for quantifying nucleic acids in a variety of research fields ranging from agricultural biology to molecular diagnostics. Because factors such ...

Scientists from the Jawaharlal Nehru Centre For Advanced Scientific Research (JNCASR) have identified a new route to ...

It uses the fact that denatured nucleic acids will bind to nitrocellulose or nylon membranes ... This immobilizes the DNA fragments, allowing specific sequences to be identified by hybridization with ...

Researchers at JNCASR have identified unique DNA structures in MPV genome that enable precise diagnostic and therapeutic strategies.