Researchers used mitochondrial gene editing to model genetic disorders in mice, revealing profound impacts on brain function, ...

Mitochondria possess their own DNA (mtDNA), which plays important roles in cellular respiration and energy consumption.

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in 1 out of every 5,000 ...

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 ...

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells ...

In the trial, 20% of patients didn’t respond well to the PCSK9 inhibitor—could genetic markers be used to tailor therapy?

While many arise from single nucleotide variations, indels, or structural variants, some forms are also triggered by repeat expansions in nuclear genes affecting mitochondrial function, which can ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

The Mito-rOCR assay measures cells’ relative oxygen consumption rate (rOCR), enabling sensitive detection of changes in ...