This useful study presents findings on how some antibiotics, which inhibit protein synthesis in bacteria, affect the translation in mitochondrial ribosomes. The authors provide solid evidence that ...

Scientists have discovered that tRNAs can determine how long mRNAs exist in a cell, causing some messages to be stabilized ...

Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...

including a small genome and a mitochondrial translation system, which reveal beyond a doubt that they originated from a specific bacterial group, the a-proteobacteria. Many bacterial genes were ...

As a team we are dedicated to improve the life of patients with mitochondrial disease by understanding the mechanisms underlying these maladies that have no treatment option to date.

Mitochondrial diseases are often caused by mutations in enzymes required for the expression of the second genome in our cells, the mitochondrial DNA. The genes encoded in the mtDNA are strictly ...