As a team we are dedicated to improve the life of patients with mitochondrial disease by understanding the mechanisms underlying these maladies that have no treatment option to date.

Mitochondrial diseases are often caused by mutations in enzymes required for the expression of the second genome in our cells, the mitochondrial DNA. The genes encoded in the mtDNA are strictly ...

Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...