Researchers used mitochondrial gene editing to model genetic disorders in mice, revealing profound impacts on brain function, metabolism, and thermoregulation.
Researchers employed a programmable DNA base editing technology to introduce a knockout mutation in the ND5 mitochondria gene, aiming to investigate the resulting genotypic and phenotypic changes.
Mitochondria are often referred to as the energy factories of cells, generating ATP that the body employs for numerous tasks. Nonetheless, our mitochondria’s operation tends to deteriorate as we ...