The microtubule-associated protein XMAP215 promotes ... which catalyse the addition of multiple actin monomers to the growing end of actin filaments. So, tip-tracking by a processive polymerase ...

In nondividing cells, microtubule networks radiate out from the centrosome to provide the basic organization of the cytoplasm, including the positioning of organelles. The protein actin is ...

This release of actin may be important for allowing the complex to adopt its more functional, microtubule-like shape. While this study reveals critical steps in how cells build their internal ...

This release of actin may be important for allowing the complex to adopt its more functional, microtubule-like shape. While this study reveals critical steps in how cells build their internal ...

With cryo-EM, they were able to see how multiple copies of CDK5RAP2 bind around the outside of the cone-shaped γTuRC, allowing it to adopt a form that can efficiently start microtubule growth. The ...