Throughout the Cancer Metabolism and the Tumour Microenvironment meeting there will be an emphasis placed not only on the mechanisms underlying the metabolic crosstalk established between cancer ...

A study uncovers how cancer cells adapt to low-glucose environments, resisting chemotherapy by conserving uridine nucleotides ...

Many cancer drugs are antimetabolites, which interfere with the cellular processes necessary for tumor growth and survival.

Published in the journal Nature Metabolism online November 26, study results showed that the low-glucose environment ...

Laboratory experiments with cancer cells have revealed two ways in which tumors evade drugs designed to starve and kill them.

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...

Discover how cancer cells survive in low-glucose environments and evade chemotherapy-induced death. New study sheds light on ...

The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in ...

Study uses spatial transcriptomics to map intratumoral heterogeneity and microenvironmental dynamics in triple-negative ...

Laboratory experiments with cancer cells reveal two ways in which tumors evade drugs designed to starve and kill them, a new ...

A metabolite transporter within the tumor microenvironment that blocks a key type of tumor cell death integral to immune response. "Tumor cells adapt their metabolic mechanisms to evade immune ...

Notably, these metabolites may also stimulate immune cell function within the tumor microenvironment, offering another pathway through which microbiome-targeted therapies might benefit PDAC patients.