For this study, Boissy and his team developed a human skin substitute model using a combination of keratinocytes and melanocytes derived from donated light and dark skin. These mixed cells were ...
He found that the pigment producing cells in the skin, called melanocytes, failed to differentiate in regions that corresponded to the location of the light-colored stripe. The melanocytes that fail ...
There were no personal or family histories of malignant melanoma. Skin examination ... papule with ill-defined light brown to pink medial and lower borders, and a dark-brown central area localized ...