Adipocyte/macrophage FABPs, A-FABP and E-FABP act ... A-FABP inhibitor BMS309403 bound to human A-FABP. FABP-mediated lipid metabolism is closely linked to both metabolic and inflammatory ...

Macrophages are particularly vulnerable to lipid-induced toxicity in the setting of metabolic diseases such as diabetes and hyperlipidemia, where the lipid concentration, composition or both are ...

In AKI, immune cells known as macrophages produce lipid mediators (LMs), which are lipids with significant physiological ...

In a paper published in Science Bulletin, multi-omics analyses comprising of lipidomics (439 lipids), sterolomics (22 ...

The experiments showed that CePA could inhibit lipid metabolism in hepatocytes by ... improve the activation and infiltration of liver macrophages during the occurrence and development of MASH ...

This study demonstrates that global or adipose tissue-specific knockout of CIDEC/FSP27 significantly reduces AAA incidence ...