Cyclin-dependent kinases (CDKs) are protein kinases involved ... First, it is quite likely that all of these proteins are activated by cyclins or cyclin-related proteins, many of which are still ...

Cyclin-dependent kinases (CDKs) trigger the transition from G1 to S phase and from G2 to M phase by phosphorylating distinct sets of substrates. (B) CDK1 and CDK2 bind to multiple cyclins (cyclin ...

Existing methods of targeting cyclin-dependent kinases, which are crucial for cell ... creating macrocycle therapies that ...