Factor IXa then moves into the intrinsic pathway and combines with ... Thus, the end product of both the extrinsic and intrinsic coagulation systems is thrombin. Since thrombin is the central ...

Under homeostatic conditions, the body is maintained in a finely tuned balance of coagulation and fibrinolysis. See Figure 1 for a depiction of normal hemostasis. The activation of the coagulation ...

Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...