Cells producing interleukin-6 (IL-6) and the actions of IL-6 in the body. Ig = immunoglobulin, CRP = C-reactive protein, SAA = serum amyloid A protein. Reprinted, with permission, from reference 21.

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6 ... a novel IL-6R inhibitor, may be beneficial for the treatment of RA in ...

Bristol–Myers Squibb (BMS) has entered a potential ∼US$1 billion agreement with Alder Biopharmaceuticals involving Alder's lead drug ALD518, a humanized monoclonal antibody specific for ...

In an interview with Ophthalmology Times, Alon Kahana, MD, PhD, discusses interleukin-6 and its role in autoimmune diseases, particularly thyroid eye disease, noting that a promising alternative under ...

Interleukin-6 IL-6 inhibitors aid neurological disorders by reducing inflammation and immune system overactivity in the brain, alleviating symptoms and slowing disease progression in conditions ...

"But we need more data to support the regular use of interleukin-6 inhibitors. We also want to thank Narcisa Hannerz and Sabine Gillsund from Karolinska University Library for their invaluable ...

By 2022, new TNF inhibitor prescriptions accounted for only 27.8% of the total. Among other biologic drugs, relatively small ...

Corvidia’s lead drug candidate – interleukin-6 inhibitor ziltivekimab (formerly COR-001) – is being developed as a therapy for reducing the risk of cardiovascular problems in CKD who have ...