To a certain extent, even in the absence of insulin signaling the body is capable of responding to fluctuations in glucose and other energy molecules 3. Clearly, other pathways sense the energy ...

The research utilizes high-level data from sources like UniProt and Gene Ontology, combined with experimental findings, to pinpoint molecules involved in leptin and insulin interaction pathways.

In addition, there is evidence that in type 2 diabetes, the activation of these same pathways by elevations in glucose and free fatty acid (FFA) levels leads to both insulin resistance and ...

Scientists discover how the Fas-p53 pathway sabotages energy metabolism, offering new hope for tackling obesity and improving insulin sensitivity. Brief Communication: Expression of p53 in human ...