Low BP or heart rate, or fluid retention: may start at 10mg once daily. Switching from immediate-release carvedilol: see literature. ≥65yrs: switching from highest dose of immediate-release ...

Carvedilol has the capacity to block both the β-1 and β-2 adrenergic receptors, as well as the α-1 receptors. There is evidence to indicate that full adrenergic blockade by carvedilol improves ...