表达IgM-BCR和IgD-BCR的初始型B细胞负责初次抗体反应，而表达IgG-BCR的记忆性B细胞主要在抗原再次暴露时产生高滴度高亲和力的IgG型的记忆性抗体反应。

Over the past decade, several features of the B-cell receptor (BCR) complex have emerged as major markers for prognostic classification of B-cell chronic lymphocytic leukemia (B-CLL). In ...