Use with GEL-FLOW NT: reconstitute Thrombin-JMI 5000 IU powder with 5mL sterile isotonic ... these may cross-react with human factor V and lead to its deficiency. Do not re-expose patients if ...

Four years ago, protein drug developer Zymogenetics in Seattle began developing a recombinant version of the blood-clotting protein thrombin. On 17 January, it received US marketing approval for ...

In view of all these facts it seemed worth while to investigate whether agents other than thrombin were capable of inducing viscous metamorphosis in normal human blood platelets.