Once inside the body, HIV persists because of its remarkable ability to hide within healthy CD4 T cells, where it can lie ...

Modern therapies help people living with HIV to survive, but scientists are still trying to decipher the deep mystery of how ...

The CCR5Δ32 variant reduces the expression of CCR5 receptors on CD4 + T cells, which HIV commonly uses to enter cells.

Preventing HIV cell entry There is no cure for AIDS ... Currently, several antiviral drugs that target cellular receptors for HIV are also under investigation. For example, Tanox's (Houston ...

CCR5 is the most commonly used receptor by HIV-1 - the virus strain of HIV that dominates around the world - to enter cells. But a very small number of people who are resistant to HIV have two ...

HIV-1 entry into cells is an attractive target for new antiviral agents. But will inhibitors aimed at the CCR5 co-receptor force HIV-1 to evolve more virulent forms? Other targets for entry ...

CCR5 is the most commonly used receptor by HIV-1 - the virus strain of HIV that dominates around the world - to enter cells. But a very small number of people who are resistant to HIV have two ...

His work indicates that this effect is mediated by activation of dopamine receptors present on the macrophage ... In the CNS, these cells are the primary targets for HIV, and their response to HIV ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...