Preventing HIV cell entry There is no cure for AIDS ... Currently, several antiviral drugs that target cellular receptors for HIV are also under investigation. For example, Tanox's (Houston ...

HIV-1 entry into cells is an attractive target for new antiviral agents. But will inhibitors aimed at the CCR5 co-receptor force HIV-1 to evolve more virulent forms? Other targets for entry ...

A dozen pharmaceutical companies, however, are developing drugs designed to block HIV's entrance into the white blood cell by creating a non-functional CCR-5 receptor. Already, some of them are in ...

Coreceptors are responsible for a crucial step between Env binding to the receptor CD4 and membrane fusion mediated by the gp41 fusion peptide. Determinants of HIV cell tropism & chemokine ...

The CCR5Δ32 variant reduces the expression of CCR5 receptors on CD4 + T cells, which HIV commonly uses to enter cells. Individuals carrying this variant exhibited lower CCR5 expression and lower ...

CCR5 is the most commonly used receptor by HIV-1 - the virus strain of HIV that dominates around the world - to enter cells. But a very small number of people who are resistant to HIV have two ...

CCR5 is the most commonly used receptor by HIV-1 - the virus strain of HIV that dominates around the world - to enter cells. But a very small number of people who are resistant to HIV have two ...

As the science stands, the vast majority of the roughly eight million people in South Africa living with HIV will have to get ...

The CCR5Δ32 variant reduces the expression of CCR5 receptors on CD4 + T cells, which HIV commonly uses to enter cells. Individuals carrying this variant exhibited lower CCR5 expression and lower rates ...

Highly effective treatments for HIV have existed since the mid-1990s. But while these treatments keep people healthy, we do not yet have a safe and scalable way to completely rid the body of the virus ...