匹兹堡大学医学中心Jeremy Rich教授团队在Cell Metabolism杂志上发表了题为Metabolic regulation of the glioblastoma stem cell epitranscriptome by malate dehydrogenase 2的论文。

A team led by researchers at the University of Toronto has uncovered new targets that could be the key to effectively ...

Six main cell types form glioblastomas (GBM), the most aggressive brain cancer due to its high rate of recurrence. Of these six, quiescent cancer stem cells are responsible for resistance to therapy ...

Her team's findings could prove highly impactful because brain tumor stem cells (BTSCs) are at the very core of therapeutic resistance and tumor recurrence in glioblastoma, a devasting and ...

These targets were identified through a screen for genetic vulnerabilities in patient-derived cancer stem cells that represent the variability found in tumours. Glioblastoma is the most common ...

Immunostaining (in green) for the Ca2+ activated chloride channel TMEM16B on patient derived glioma stem cells. The blue ...