These targets were identified through a screen for genetic vulnerabilities in patient-derived cancer stem cells that represent the variability found in tumors. Glioblastoma is the most common type of ...

A team led by researchers at the University of Toronto has uncovered new targets that could be the key to effectively ...

Aug. 12, 2024 — Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro ...

Her team's findings could prove highly impactful because brain tumor stem cells (BTSCs) are at the very core of therapeutic resistance and tumor recurrence in glioblastoma, a devasting and ...

These targets were identified through a screen for genetic vulnerabilities in patient-derived cancer stem cells that ...

It is also the most challenging to treat due to the resistance of glioblastoma cancer stem cells, from which tumors grow, to therapy. Cancer stem cells that survive after a tumor is treated go on ...