Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...
determined that maintaining highly proliferative stem cells is perhaps the single ... induce Pax-6 expression — a marker for radial glial cells in the cortex. This resulted in a very pure ...
Glial restricted precursors maintain their permissive properties after long-term ... 2014 Promising advances in targeted cellular based therapies: Treatment update in spinal cord injury. Journal of ...
The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms. Over the last decade, Dr.
We use pluripotent stem cells to model neurological development and disease with a specific focus on glial cells in the central nervous system – oligodendrocytes and astrocytes. We are interested in ...
Donald and Ruth Weber Goodman Professor of Innovative Therapeutics in the School of Medicine's Department of Genetics and Genome Sciences—began when he conducted groundbreaking stem-cell research as a ...
His lab has built an interdisciplinary research program that draws on paradigms from development, disease, physiology, and genomics to better understand the nature of glial cells in the brain. Bruno ...