STI571 (imatinib mesylate; Gleevec) is a selective inhibitor of ... chronic myelogenous leukemia and gastrointestinal stromal tumors. The authors report the case of male patient age 63 years ...

How do scientists develop new treatments for disease? With Gleevec, a remarkable cancer drug, the approach was to target the disease at the cellular and subcellular level. When people say Gleevec ...

While no pretherapy exploratory laparotomy was performed, we hypothesize that the shrinkage of the primary tumor led to a generalized inflammatory response around the kidney, which caused the ...