Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors and were among the first solid tumor types for which such a novel treatment (in this case imatinib) became available. The ...

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these ...

Background Gastrointestinal stromal tumor (GIST) is known for its wide variability in biological behaviors and it is difficult to predict its malignant potential. The aim of this study is to ...

11月 3 日，中国科学院上海营养与健康研究所王跃祥团队、华大 基因智惠医学 研究院吴逵团队和上海交通大学附属仁济医院曹晖团队在 Nature Communications 在线发表了题为 Genomic and Transcriptomic Landscape of Human Gastrointestinal Stromal Tumors 的 ... 基因YLPM1, 为GIST的发病机制 ...

【导读】胃肠道间质瘤（GIST）在临床上具有异质性，在个体患者中表现出不同程度的疾病侵袭性。团队全面描述了117例GIST队列的基因组和转录组学景观，包括来自105例患者的31例低风险、18例中危、29例高风险、34例转移性和5例新辅助GIST。20 ...

Here are some soft-tissue sarcomas of the abdomen: Gastrointestinal stromal tumor (GIST) usually forms in the stomach or small intestine. Leiomyosarcoma most commonly forms in the uterus. It can also ...

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these ...

More information: Feifei Xie et al, Genomic and transcriptomic landscape of human gastrointestinal stromal tumors, Nature Communications (2024). DOI: 10.1038/s41467-024-53821-1 Provided by BGI ...

DelveInsight’s “Gastrointestinal Stromal Tumor Market Insights, Epidemiology, and Market Forecast-2034″ report offers an in-depth understanding of the Gastrointestinal Stromal Tumor, historical and ...

Combination of ziftomenib and imatinib shows robust and durable antitumor activity in imatinib-sensitive (1L) and imatinib-resistant (2L/3L) GIST models – – Proof-of-concept study of ziftomenib plus ...