Epistasis describes how gene interactions can affect phenotypes. Did you know that genes can mask each other's presence or combine to produce an entirely new trait? But what happens when two ...

Understanding the causes and genetic basis behind these diseases proved elusive when using single-gene studies. However, now that there is a greater focus on epistatic interactions, there may be ...

This study provides a valuable look at genome-wide RNaseA-resistant RNA-DNA interactions in human embryonic stem cells. The research indicated that RNase treatment maintained long-range RNA-chromatin ...

but two other newly described important types of interactions also exist: drug–gene interactions (DGIs) and drug–drug–gene interactions (DDGIs). A drug–gene interaction occurs when a ...

Multiplexed assays of variant effect are an increasingly important tool in genetic research and including more context specificity in their design would aid interpretation and discovery.

The University of Alabama at Birmingham, The Northern California Cancer Center, The University of Missouri-Rolla. The Center is focused on the role that diet plays in the programming of genes that are ...

A study published in October 2024 in the journal Molecular Psychiatry found that brain volume changes correlate with social ...

An international research collaboration has shed new light on the molecular basis of gene expression, the fundamental biological process that underpins how all organisms use their genetic information.