To maximize the potential of the mouse as a model organism, we now face challenges that go beyond simply establishing a mutant line for every gene. The focus of genetic research for the next ...

Mouse phenotyping studies analyse biological properties, such as the evolution of disease symptoms, in mice that have had a specific gene modified ... the Korean Animal Model Archive to help ...

Investigators from New York State Office for People with Developmental Disabilities (OPWDD) and affiliated organizations have reported the discovery and preclinical characterization of a gene therapy ...

As part of this analysis, we observed that in many instances, a small subset of tumors or cancer cell lines harboring an oncogenic gene fusion displays characteristic amplification at the site of ...

The mouse on the left is a chimeric with dark eyes and patches of black fur, a result of stem cells derived from a choanoflagellate Sox gene. The wildtype mouse on the right has red eyes and all ...