and fibrotic granulomas in the lungs of patients with chronic Mycobacterium tuberculosis infection. In addition to being an important pathogenic mechanism, stromal-immune cell interaction can also ...

(x 100) F: Morpheic subtype, a variant of infiltrative basal cell carcinoma, wherein the tumor cells are embedded in a dense fibrotic stroma. (x 100) (all cases stained with hematoxylin-eosin) ...

and diverse molecular- and cell-biological techniques enabling investigation of the mechanisms underlying tumor-stroma interaction. Into the Matrix: MSK’s Mara Sherman is Unlocking the Secrets of the ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

(a) Hematoxylin and eosin (H&E) stain (100×) on a needle biopsy specimen showing clusters of epithelioid tumor cells in a fibrotic stroma. (b) Corresponding area to (a) with positive nuclear and ...