and day 3 am and pm assessments), achieving significance versus fexofenadine as early as 12 hours following the first dose (day 1 pm). Median times to a 25% reduction and maximum reduction in am ...

Eight-hundred and thirty-six patients were randomised to therapy at 25 sites in the United States and received at least one dose of loratadine (n = 357), fexofenadine (n = 360) or placebo (n = 119).