and 12 events per 100 patient-years of exposure for the febuxostat 80-mg, febuxostat 120-mg, and allopurinol groups, respectively. Serious adverse events were reported by 161 patients, with ...

Febuxostat 40 mg daily appears to be as efficacious as allopurinol in lowering serum uric acid levels. [38] Both febuxostat 40 and 80 mg can be given to patients with mild-to-moderate renal impair ...